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When they fed on malaria-infected mice, the resistant mosquitoes had a higher survival rate than nonresistant ones, meaning they could eventually replace the ones that can carry the disease, according to a report in Tuesday’s issue of Proceedings of the National Academy of Sciences

2018년 11월 11일When they fed on malaria-infected mice, the resistant mosquitoes had a higher survival rate than nonresistant ones, meaning they could eventually replace the ones that can carry the disease, according to a report in Tuesday’s issue of Proceedings of the National Academy of Sciences.

Jason Rasgon of the department of molecular microbiology and immunology at Johns Hopkins University cautioned that the research so far is only a proof of principle and any field tests remain far away.

Nonetheless, it’s a goal eagerly sought by scientists in hope of developing a practical way of blocking the spread of malaria.

According to the federal Centers for Disease Control and Prevention, an estimated 700,000 to 2.7 million people die of malaria each year, 75 percent of them African children.

Working with the mouse form of malaria — not the human type — Rasgon’s team was able to genetically engineer mosquitoes that were resistant to malaria.

Malaria infection does exact a toll on mosquitoes and in laboratory work they found that the resistant insects were able to outcompete nonresistant mosquitoes.

Starting with the same number of resistant and nonresistant mosquitoes, they found that after nine generations, the resistant type made up 70 percent of the population — raising the possibility of replacing regular mosquitoes with resistant ones that don’t spread disease.

However, Rasgon stressed that in the lab work the insects were infected with a higher amount of the parasite than occurs in nature, and a larger proportion of the mosquitoes were infected.

«This was proof of principle,» Rasgon said in a telephone interview. «The next step would be to work in a system more epidemiologically relevant» but still in the lab.

«We’re not anywhere near a field release,» he said. Now they need to turn their attention to working with human malaria and trying to engineer a mosquito resistant to that.

William C. Black IV, 장흥출장안마 a professor of entomology at Colorado State University, noted that the work was done with Plasmodium berghei, which infects mice, rather than P. falciparum, which causes malaria in humans.

P. berghei is often used in laboratory work because it is easy to manipulate, but a lot of its properties are specific to that parasite and it is not always a good model for the human form, he said.

«On the other hand, finding a gene that confers resistance and is stable for a long period of time is significant,» said Black, who was not part of the research team.

If they can repeat the work using the human parasite then there is a chance of taking it into the field, he said.

Dr. Woodbridge A. Foster, an entomologist at Ohio State University who was not part of the research team, said that while several labs have been trying to develop a resistant mosquito, he was not aware of any that had been developed that were both healthy and inhospitable to the malaria parasite.

Rasgon’s research was funded by the National Institutes of Health.

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There were no injuries, though both caused some damage to buildings and knocked out the signal of the Televisa network for several hours

The prosecutor, Roberto Jaime Suarez, disappeared Wednesday in the town of San Fernando, where the bodies of the migrants were found, the Tamaulipas state attorney general’s office said in a statement. A transit police officer in the town is also missing.

President Felipe Calderon, speaking during a forum on security, said Suarez, a Tamaulipas state prosecutor, was involved in the initial investigation of the massacre, which authorities have blamed on the Zetas drug cartel. The federal Attorney General’s Office has since taken the lead in the case.

Mexico Massacre Survivor Describes Grisly SceneDrug Cartel Suspected in Massacre of 72 MigrantsTwo Bodies Hung from Bridge on Road to AcapulcoMexican Mayor Found Dead 3 Days after Kidnapping

The two car explosions happened less than 45 minutes apart in Ciudad Victoria, the Tamulipas state capital, the Attorney General’s Office said. The first exploded in front of the offices of the Televisa network and the second in front of transit-police offices.

There were no injuries, though both caused some damage to buildings and knocked out the signal of the Televisa network for several hours. The explosion outside Televisa was felt for several blocks.

The network described the explosion as a car bomb, but the state attorney general’s office said the cause of the explosions have not been determined.

If confirmed, it would mean a total of four car bombs in Mexico this year — a new and frightening tactic in the country’s escalating drug war.

The first exploded July 5 in the northern border city of Ciudad Juarez, across the border from El Paso, Texas, killing a federal police officer and two other people. The second, which caused no injuries, happened just two weeks ago in front of police headquarters in Ciudad Victoria.

Just north of Ciudad Victoria, heavily guarded investigators working at a private funeral home in San Fernando identified 31 of the 72 massacred migrants, whose bodies were discovered on a ranch Tuesday, bound, blindfolded and slumped against a wall.

Those identified include 14 Hondurans, 12 Salvadorans, four Guatemalans and one Brazilian, the state attorney general’s office said.

By Associated Press Writer E. Eduardo Castillo. Alexandra Olson, Isaac Garrido and Katherine Corcoran in Mexico City; Gonzalo Solano in Quito, Ecuador; Diego Mendez in San Salvador, El Salvador; and Freddy Cuevas in Tegucigalpa, Honduras, 영덕출장안마 contributed to this report

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The baby’s doing great and happy and healthy, and it’s a really joyful time,» she added

티켓다방 이마담의 영업방식Like any other proud grandmother, Kris Jenner is happy to gush about daughter Kim Kardashian and hernew baby girl, 군산출장안마 North West.

Appearing on the «Today» show Tuesday, Jenner said baby North West, who is just over a week old, is «amazing.»

«Everybody’s doing really well at home. … The baby’s doing great and happy and healthy, and it’s a really joyful time,» she added.

Later Tuesday, while appearing on «The View,» Jenner explained the significance of her granddaughter’s compass-inspired name.

«I love the name North,» Jenner said of her third grandchild’s moniker. «I’m pro-North, absolutely. The way [Kim] explained it to me was that North means Highest Power, and she says that North is their highest point together. And I thought that was really sweet.»

Jenner was making the media rounds to promote her upcoming talk show, «Kris,» which premieres July 15.

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